GSK-9772
CAS No. : 928035-84-1
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| Cat. No. : | HY-14353 |
| M.Wt: | 490.27 |
| Formula: | C20H19Cl2F6NO2 |
| Purity: | >98 % |
| Solubility: |
GSK-9772 is a Liver X Receptor (LXR) modulator of the N-phenyl tertiary amine class (NPTAs) with high affinity for LXR β ligand (IC50=30 nM). GSK-9772 has anti-inflammatory activity by binding to LXR, specifically by interacting with the region associated with the transcriptional repression function of the receptor, thereby inhibiting the expression of pro-inflammatory genes. GSK-9772 can be used in the study of inflammatory and neurodegenerative diseases[1].
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