Ecamsule


CAS No. : 92761-26-7

92761-26-7
Price and Availability of CAS No. : 92761-26-7
Size Price Stock
5mg $75 In-stock
10mg $120 In-stock
25mg $238 In-stock
50mg $357 In-stock
100mg $536 In-stock
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Cat. No. : HY-16182
M.Wt: 562.69
Formula: C28H34O8S2
Purity: >98 %
Solubility: Ethanol : 50 mg/mL (ultrasonic);Methanol : 31.25 mg/mL (ultrasonic)
Introduction of 92761-26-7 :

Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) [1] [2]. In Vitro: Ecamsule is a broad-spectrum UVA-absorber with maximum absorbance at 344 nm[1].
Wild-type Fibs E6/E7 cells are more sensitive towards Ecamsule (200-1600 μM) treatment[1].
. Ecamsule counteractes UV and AAPH induced ROS-formation[1].
. The effects are dose-dependent, reaching a maxi-mum ROS reduction by 25.7% at the highest tested concentration of 1600 μM in the UV-setting. With the same concentration of Ecamsule, oxidative stress that had been trigged by AAPH is reduced by 10.8% and basal levels are attenuated by 16.9%[1].
. Ecamsule increases the viability at the highest applied concentration of 1600 μM in the AAPH-treated cells[1].

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