LSD1-IN-2
CAS No. : 927019-63-4
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| Cat. No. : | HY-124961 |
| M.Wt: | 328.51 |
| Formula: | C15H36N8 |
| Purity: | >98 % |
| Solubility: |
LSD1-IN-2 is a LSD1 inhibitor with an IC50 of 0.5 μM. LSD1-IN-2 increases the levels of monomethylated and dimethylated histone H3 lysine 4 (H3K4me1/2) in cells. LSD1-IN-2 reactivates epigenetically silenced tumor suppressor genes. LSD1-IN-2 can be used in the research of colon cancer[1].
In Vitro:LSD1-IN-2 (Compound 39) potently inhibits LSD1 with an IC50 of 0.5 μM[1].
LSD1-IN-2 (0.5-10 μM) induces dose-dependent increases in H3K4me1/2 levels and tumor suppressor gene re-expression in HCT-116 colon cancer cells[1].
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