AS115


CAS No. : 926657-43-4

926657-43-4
Price and Availability of CAS No. : 926657-43-4
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Cat. No. : HY-114056
M.Wt: 381.48
Formula: C21H32FNO4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 926657-43-4 :

AS115 is a potent and selective KIAA1363 inactivator with IC50 value of 150 nM. KIAA1363 is a 2-acetyl monoacylglycerol ether (MAGE) hydrolase that is upregulated in aggressive cancers of various tissues[1][2]. In Vitro:AS115 (10 μM, 4 h) can significantly reduce the formation of MAGE, alkyl lysophosphatidylcholine and alkyl lysophosphatidic acid in SKOV3 cells[1].

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