EC-0225
CAS No. : 926626-77-9
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| Cat. No. : | HY-16181 |
| M.Wt: | 2192.51 |
| Formula: | C103H130N20O26S4 |
| Purity: | >98 % |
| Solubility: |
EC-0225, a folate conjugate of two agents- one a potent microtubule inhibiting agent, and the second a DNA alkylating agent. EC-0225 inhibits the growth of folate receptor (FR)-positive KB cells with an IC50 of ~1 nM. EC-0225 can be selectively delivered to advanced FR-positive tumors without causing overt toxicity, such as lung carcinoma[1].
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