HA-1004 (hydrochloride)
CAS No. : 92564-34-6
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| Cat. No. : | HY-112348 |
| M.Wt: | 329.81 |
| Formula: | C12H16ClN5O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
HA-1004 hydrochloride is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 hydrochloride is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein (Cyclic GMP-AMP Synthase), and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 hydrochloride an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models[1][2][3][4].
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- HA-1004 (hydrochloride)
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