Lagociclovir


CAS No. : 92562-88-4

(Synonyms: MIV-210)

92562-88-4
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Cat. No. : HY-14844
M.Wt: 269.23
Formula: C10H12FN5O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 92562-88-4 :

Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV[1]. IC50 & Target:HBV[1] In Vitro:Lagociclovir (FLG) (6 days) shows inhibitory activity with IC50s of 8 ± 3.8, 9 ± 2.5, 13 ± 3.4 and 15 ± 6.8 μM against 3TC-R HBV, wt HBV, PMEA-R HBV and 3TC+PMEA-R HBV, respectively in transiently transfected Huh7 cells[1].
Lagociclovir (0-100 μM; 6 days) inhibits the replication of wild-type and drug-resistant mutants of HBV in transiently transfected Huh7 cells[1].

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