| Size | Price | Stock |
|---|---|---|
| 1mg | $534 | Get quote |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-14844 |
| M.Wt: | 269.23 |
| Formula: | C10H12FN5O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV[1].
IC50 & Target:HBV[1]
In Vitro:Lagociclovir (FLG) (6 days) shows inhibitory activity with IC50s of 8 ± 3.8, 9 ± 2.5, 13 ± 3.4 and 15 ± 6.8 μM against 3TC-R HBV, wt HBV, PMEA-R HBV and 3TC+PMEA-R HBV, respectively in transiently transfected Huh7 cells[1].
Lagociclovir (0-100 μM; 6 days) inhibits the replication of wild-type and drug-resistant mutants of HBV in transiently transfected Huh7 cells[1].
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