Jingzhaotoxin-III


CAS No. : 925463-91-8

(Synonyms: β-TRTX-Cj1α)

925463-91-8
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Cat. No. : HY-P1219
M.Wt: 3919.45
Formula: C174H241N47O46S6
Purity: >98 %
Solubility: H2O
Introduction of 925463-91-8 :

Jingzhaotoxin-III is a potent and selective blocker of Nav1.5 channels, with an IC50 of 348 nM, and shows no effect on other sodium channel isoforms. Jingzhaotoxin-III can selectively inhibit the activation of cardiac sodium channel but not neuronal subtypes, and hopefully represents an important ligand for discriminating cardiac VGSC subtype[1][2]. IC50 & Target:IC50: 348 nM (Nav1.5 Channels)[1]

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