DUB-IN-2
CAS No. : 924296-19-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $169 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $663 | In-stock |
| 100mg | $1060 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-50737A |
| M.Wt: | 275.26 |
| Formula: | C15H9N5O |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic) |
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8[1]. IC50 & Target: IC50: 0.28 μM (USP8)[1] In Vitro: DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM[1].
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