DUB-IN-1
CAS No. : 924296-18-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $240 | In-stock |
| 10mg | $390 | In-stock |
| 25mg | $750 | In-stock |
| 50mg | $1050 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-50736 |
| M.Wt: | 337.33 |
| Formula: | C20H11N5O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs), with an IC50 of 0.85 μM for USP8[1]. IC50 & Target: IC50: 0.24 μM (USP8)[1] In Vitro: DUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC50, >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50s ranging from 0.5 μM to 1.5?μM[1].
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