Dulaglutide
CAS No. : 923950-08-7
(Synonyms: LY2189265)
| Size | Price | Stock |
|---|---|---|
| 1mg | $270 | In-stock |
| 5mg | $800 | In-stock |
| 10mg | $1360 | In-stock |
| 25mg | $2500 | In-stock |
| 50mg | $4000 | In-stock |
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| Cat. No. : | HY-P0120 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Dulaglutide (LY2189265) is a glucagon-like peptide-1 (GLP-1) receptor agonist. Dulaglutide can be uesd for the research of type 2 diabetes (T2D) [1][2].
IC50 & Target:GLP-1 receptor[1]
In Vitro: Dulaglutide (50 nM and 100 nM; 24 h) ameliorates ox-LDL-induced oxidative stress and suppresses ox-LDL-induced mitochondrial dysfunction in human aortic endothelial cells (HAECs)[1].
In Vivo: Dulaglutide (0, 0.05, 0.5, 1.5, or 5 mg/kg; s.c.; twice week, for 93 weeks) increases the incidence of thyroid C-cell hyperplasia and neoplasia in the rat carcinogenicity study[2].
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