Refametinib (R enantiomer)


CAS No. : 923032-38-6

(Synonyms: BAY 869766 R enantiomer; RDEA119 R enantiomer)

923032-38-6
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Cat. No. : HY-10216
M.Wt: 572.34
Formula: C19H20F3IN2O5S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 923032-38-6 :

Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM. IC50 & Target: EC50: 2.0-15 nM (MEK)[1] In Vitro: Refametinib R enantiomer is the R enantiomer of Refametinib . Refametinib R enantiomer is an inhibitor of MEK and is useful in treatment of cancer and other hyperproliferative diseases[1].

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