CAS No. : 923032-38-6
(Synonyms: BAY 869766 R enantiomer; RDEA119 R enantiomer)
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|---|---|---|
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| Cat. No. : | HY-10216 |
| M.Wt: | 572.34 |
| Formula: | C19H20F3IN2O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM. IC50 & Target: EC50: 2.0-15 nM (MEK)[1] In Vitro: Refametinib R enantiomer is the R enantiomer of Refametinib . Refametinib R enantiomer is an inhibitor of MEK and is useful in treatment of cancer and other hyperproliferative diseases[1].
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