Fotemustine
CAS No. : 92118-27-9
(Synonyms: S10036)
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| Cat. No. : | HY-B0733 |
| M.Wt: | 315.69 |
| Formula: | C9H19ClN3O5P |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 3.2 mg/mL |
Fotemustine is a DNA-alkylating agent, with antitumor activity. IC50 & Target:DNA Alkylator[1] In Vitro:Fotemustine is a DNA-alkylating agent. Fotemustine (800 μM) decreases GSH and intracellular GSSG levels but increases the extracellular GSSG-levels rapidly in isolated rat hepatocytes[1]. Fotemustine shows inhibitory effect on several tumor cell lines, with IC50s ranging form 0.05 to 0.18 mM[2].
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