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|---|---|---|
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| Cat. No. : | HY-113514 |
| M.Wt: | 276.14 |
| Formula: | C6H13O10P |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite[1][2]. IC50 & Target:PGI[1] In Vitro: 6-Phosphogluconic acid (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1].
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