Phenidone
CAS No. : 92-43-3
| Size | Price | Stock |
|---|---|---|
| 100g | $47 | In-stock |
| 500g | $165 | In-stock |
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| Cat. No. : | HY-W010144 |
| M.Wt: | 162.19 |
| Formula: | C9H10N2O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 3.33 mg/mL (ultrasonic;warming;heat to 60°C) |
Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3]. In Vitro: Phenidone significantly inhibits the increases in COX-1/-2 and 5-LOX in the spinal cords of rats with experimental autoimmune encephalomyelitis (EAE)[1]. In Vivo: Phenidone inhibits the formation of vascular lipoxygenase products and to reduce blood pressure in the AII-dependent renovascular hypertensive rat[2].
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