Phenyltoloxamine
CAS No. : 92-12-6
(Synonyms: Bistrimin; Histionex)
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| Cat. No. : | HY-B1733 |
| M.Wt: | 255.35 |
| Formula: | C17H21NO |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (Ki: 160 nM)[1][2][3].
In Vitro:Phenyltoloxamine (10-50 μM, 24 h) demonstrates cytotoxicity in EVSA-T cells[2].
Phenyltoloxamine exhibits potent Sigma 1 Receptor (S1R) binding affinity with a Ki value of 160 nM[3].
Phenyltoloxamine (100 μM) inhibits human liver macrosaml CYP2D6 enzyme by 99.0%[4].
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