OF-1
CAS No. : 919973-83-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $102 | In-stock |
| 10mg | $162 | In-stock |
| 25mg | $290 | In-stock |
| 50mg | $435 | In-stock |
| 100mg | $650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12518 |
| M.Wt: | 440.31 |
| Formula: | C17H18BrN3O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 13 mg/mL (ultrasonic;warming) |
OF-1 is a potent pan-BRPF bromodomain (BRD) inhibitor, with IC50 values of 270 nM, 1.2 μM for TRIM24 and BRPF1B, respectively[1][2].
In Vitro: OF-1 (1 μM and 2 μM, 0, 1, 2, and 3 days) causes significant reductions in the number of multinucleated tartrate-resistant acid phosphatase (TRAP) positive cells[1].
OF-1 is the only inhibitor to completely suppress the fusion into multinucleated “osteoclast-like” cells[1].
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