AZD1656


CAS No. : 919783-22-5

919783-22-5
Price and Availability of CAS No. : 919783-22-5
Size Price Stock
5mg $250 In-stock
10mg $400 In-stock
25mg $800 In-stock
50mg $1200 In-stock
100mg $1800 In-stock
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500 mg Get quote
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Cat. No. : HY-15675
M.Wt: 478.50
Formula: C24H26N6O5
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 919783-22-5 :

AZD1656 is a potent, selective and orally active glucokinase activator with an EC50 of 60 nM. AZD1656 has the potential for type 2 diabetes research[1][2][3]. IC50 & Target: EC50: 60 nM (Glucokinase)[2] In Vivo: AZD1656 (0-9 mg/kg; oral gavage; daily; for 8 weeks; C57BL/6 mice) treatment shows lowered blood glucose and glucose excursion and raised insulin. Liver mRNA levels for various ChREBP target genes including carbohydrate response element binding protein beta isoform (ChREBP-β), G6pc, Pklr, Acly, Acac and Gpd2 are increased by AZD1656[1].

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