Avoralstat
CAS No. : 918407-35-9
(Synonyms: BCX4161)
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $122 | In-stock |
| 25mg | $245 | In-stock |
| 50mg | $396 | In-stock |
| 100mg | $576 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-16735 |
| M.Wt: | 513.54 |
| Formula: | C28H27N5O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research[1][2]. In Vitro: C1 inhibitor (C1INH) is the primary regulator of contact activation, both by inhibiting the conversion of prekallikrein to plasma kallikrein (PKK) by FXIIa, and by directly inhibiting PKK. PKK cleaves high molecular weight kininogen, releasing bradykinin, whose actions are responsible for the signs and symptoms of hereditary angioedema (HAE)[2].
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