BL-1020 (mesylate)


CAS No. : 916898-61-8

916898-61-8
Price and Availability of CAS No. : 916898-61-8
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Cat. No. : HY-111136
M.Wt: 585.18
Formula: C26H37ClN4O5S2
Purity: >98 %
Solubility:
Introduction of 916898-61-8 :

BL-1020 mesylate is the mesylate salt form of BL-1020. BL-1020 mesylate is an antipsychotic agent. BL-1020 mesylate is inhibitor for dopamine receptor and serotonin receptor (5-HT receptor), with Ki of 0.066, 0.062 and 0.21 nM, for D2L, D2S and 5-HT2A receptors, respectively. BL-1020 mesylate is agonist for GABAA receptor with Ki of 3.74 μM, and enhances the GABA release. BL-1020 mesylate exhibits high affinity with histamine receptor (Ki is 0.47 nM). BL-1020 mesylate reduces Amphetamine-induced hyperactivity, with lower catalepsy and sedation. BL-1020 mesylate is blood-brain barrier penetrate[1].

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