CAY10595
CAS No. : 916047-16-0
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|---|---|---|
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| 10 mg | Get quote | |
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| Cat. No. : | HY-118180 |
| M.Wt: | 451.23 |
| Formula: | C20H13Cl2FN2O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CAY10595 is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM. IC50 & Target: Ki: 10 nM (human CRTH2/DP2 receptor)[1]. In Vitro: CAY10595 (compound 71) is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM[1]. In Vivo: Administration of the DP2 antagonist CAY10595 slightly delays the development of CIA. Treatment with CAY10595 reduces IgG2a anti-CII levels without modification of IgG anti-CII levels[2].
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