Piperaquine (tetraphosphate tetrahydrate)
CAS No. : 915967-82-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $45 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $135 | In-stock |
| 100mg | $205 | In-stock |
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| Cat. No. : | HY-B1896B |
| M.Wt: | 999.60 |
| Formula: | C29H32Cl2N6.4H3O4P.4H2O |
| Purity: | >98 % |
| Solubility: | H2O : 6 mg/mL (ultrasonic);DMSO : < 1 mg/mL |
Piperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. Piperaquine tetraphosphate tetrahydrate can be used in antimalarial research in combination with Artemisinin[1][2].
In Vivo: Piperaquine (10-90 mg/kg; a single i.p.) decreases parasitemia at all of the doses tested in mice[1].
Piperaquine (90 mg/kg; a single i.p.) exhibits the t1/2, apparent clearance, and apparent volume of distribution 17.8 days, 33.5 mg?h/L, 1.55 L/h/kg, and 956 L/kg, respectively, in healthy mice and 16.1 days, 27.3 mg?h/L, 1.9 L/h/kg, and 1,059 L/kg in malaria-infected mice[1].
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