Indimitecan
CAS No. : 915360-05-3
(Synonyms: LMP776)
| Size | Price | Stock |
|---|---|---|
| 5mg | $260 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $650 | In-stock |
| 50mg | $910 | In-stock |
| 100mg | $1280 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18350 |
| M.Wt: | 459.45 |
| Formula: | C25H21N3O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 8.33 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 60°C) |
Indimitecan (LMP776) is a topoisomerase I (Top1) inhibitor with anticancer activities[1].
In Vitro: Indimitecan (LMP776) (0-100 μM) shows antiproliferative potencies against various human cancer cell lines, with mean-graph midpoint (MGM) of 0.079 ± 0.023 μM[1].
Indimitecan shows potent DNA cleavage due to Top1 inhibition[1].
Indimitecan can be substrates for metabolic ketone reductases[1].
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