Rubitecan
CAS No. : 91421-42-0
(Synonyms: RFS 2000; 9-Nitrocamptothecin)
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $110 | In-stock |
| 50mg | $165 | In-stock |
| 100mg | $245 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-13744 |
| M.Wt: | 393.35 |
| Formula: | C20H15N3O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic) |
Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells[1][2][3]. IC50 & Target: Topoisomerase I[1] In Vitro: Rubitecan (RFS 2000) inhibits U-CH1, U-CH2, and CCL4 cells with IC50s 0.32, 0.83, and 7.7 µM, respectively[4].
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