Glycyl H-1152 (hydrochloride)
CAS No. : 913844-45-8
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| Cat. No. : | HY-15720B |
| M.Wt: | 449.40 |
| Formula: | C18H26Cl2N4O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride[1].
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