GSK575594A
CAS No. : 909418-68-4
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| Cat. No. : | HY-111161 |
| M.Wt: | 471.52 |
| Formula: | C24H23F2N3O3S |
| Purity: | >98 % |
| Solubility: |
GSK575594A is a modulator of the nicotinic acetylcholine receptor (nAChR) in Ascaris suum. GSK575594A enhances muscle contractions induced by acetylcholine (ACh) by binding to the allosteric binding site between subunits within the transmembrane domain of nAChR. At a concentration of 3 μM, GSK575594A significantly increased the contraction induced by ACh in Ascaris suum (Emax increased from 1.19 g to 1.51 g). GSK575594A may be used in research within the field of antiparasitic studies[1].
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