ISX-1
CAS No. : 909207-35-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $265 | In-stock |
| 10mg | $370 | In-stock |
| 25mg | $575 | In-stock |
| 50mg | $805 | In-stock |
| 100mg | $1130 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-113790 |
| M.Wt: | 302.35 |
| Formula: | C14H14N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
ISX-1 is an isoxazole. ISX-1 has anti-adipogenic and pro-osteogenic activities. ISX-1 can be used for the research of osteopenia and osteoporosis[1].
IC50 & Target:IC50: 1.9 μM (lipid droplet formation); EC50: 1.2 μM (induce ALP)[1]
In Vitro:ISX-1 dose-dependently inhibits the accumulation of intracellular lipid droplets and stimulated ALP activity[1].
ISX-1 can form lipid droplet with an IC50 value of 1.9 μM and also can induce ALP with an EC50 value of 1.2 μM[1].
ISX-1 (0, 1.3, 6.5 and 33 μM; 3 days) inhibited the mRNA induction of PPARγ and FABP4 genes under the adipogenic differentiation of hBMSCs[1].
ISX-1 (0, 1.3, 6.5 and 33 μM) promotes TCF/LEF-mediated gene transcription[1].
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