CLinDMA


CAS No. : 908860-82-2

908860-82-2
Price and Availability of CAS No. : 908860-82-2
Size Price Stock
5mg $380 In-stock
10mg $620 In-stock
25mg $1250 In-stock
50mg $2000 In-stock
100mg $3200 In-stock
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Cat. No. : HY-112763
M.Wt: 808.35
Formula: C54H97NO3
Purity: >98 %
Solubility: DMSO : 140 mg/mL (ultrasonic)
Introduction of 908860-82-2 :

CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA[1]. In Vitro: LNP201 causes sustained silencing of the murine Ssb gene in the mouse liver after single or multiple doses through an RNAi mechanism. LNP201 causes an acute inflammatory response, inducing expression of numerous genes involved in innate immunity as well as mitogen-activated protein kinase (MAPK) phosphorylation in tissues[1].

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