Neuropeptide Y (human,rat,mouse)


CAS No. : 90880-35-6

(Synonyms: Neuropeptide Y (29-64), amide)

90880-35-6
Price and Availability of CAS No. : 90880-35-6
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1mg $98 In-stock
5mg $210 In-stock
10mg $340 In-stock
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Cat. No. : HY-P0198
M.Wt: 4271.68
Formula: C189H285N55O57S
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 90880-35-6 :

Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. In Vitro: It is showed that Neuropeptide Y (human,rat,mouse) is able to protect cortical neurons from Aβ25-35 toxicity. 2 μM NPY abolishes the toxic effects of Aβ25-35 at 24 and 48 h. The same effect on neuronal survival is observed in neurons exposed to 1 μM and 0.5 μM Neuropeptide Y (human) pretreatments. Pretreatment with Neuropeptide Y (29-64), amide, human (TFA) Increases NGF Synthesis, reduces NGF mRNA, and restores NGF release in cortical neurons exposed to Aβ35-25[1].

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