Laprafylline
CAS No. : 90749-32-9
(Synonyms: S 9795)
| Size | Price | Stock |
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| 1mg | $646 | Get quote |
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| 10mg | $2142 | Get quote |
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| Cat. No. : | HY-106306 |
| M.Wt: | 500.64 |
| Formula: | C29H36N6O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Laprafylline (S 9795), a xanthine derivative, is a bronchodilator. Laprafylline has potent anti-bronchoconstrictive effects, inhibiting action on mast cell degranulation and phosphodiesterase (PDE) activity (IC50 of 6 μM)[1]. In Vivo:In male Sprague Dawley rats, Laprafylline (S 9795; 2.5-10mg/kg; iv) disappears rapidly from plasma with an elimination t1/2 of 0.8 h, regardless of the dose administered. The volume of distribution is high (about 3 L/kg) but total clearance is also high (about 40 mL/min/kg).
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