MI-223


CAS No. : 907166-59-0

907166-59-0
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Cat. No. : HY-124846
M.Wt: 419.86
Formula: C23H18ClN3O3
Purity: >98 %
Solubility:
Introduction of 907166-59-0 :

MI-223 is a Mcl-1 regulator (Kd = 160 nM). MI-223 binds to the BH1 domain, blocking Mcl-1-stimulated homologous recombination DNA repair, thus sensitizing cancer cells to DNA replication agents. MI-223 can be used in research on cancers such as lung cancer[1].

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