Motapizone
CAS No. : 90697-57-7
(Synonyms: NAT 05-239)
| Size | Price | Stock |
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| 5mg | $130 | Get quote |
| 10mg | $200 | Get quote |
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| Cat. No. : | HY-106739 |
| M.Wt: | 260.32 |
| Formula: | C12H12N4OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Motapizone (NAT 05-239) is a selective PDE3 inhibitor. Motapizone moderately inhibits cytokine release in lipopolysaccharide (LPS)-induced alveolar macrophages. Motapizone also inhibits human platelet aggregation by increasing intracellular cAMP[1][2]. In Vitro:Motapizone (10 μM; 15 min before oxidants) results 20% inhibition rate for cytokine release in lipopolysaccharide (LPS)-induced alveolar macrophages with oxidative stress conditions, but the inhibitory effect is not affected by oxidative stress[1].
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