| Size | Price | Stock |
|---|---|---|
| 1mg | $190 | Get quote |
| 5mg | $462 | Get quote |
| 10mg | $668 | Get quote |
| 25mg | $1097 | Get quote |
| 50mg | $1559 | Get quote |
| 100mg | $2136 | Get quote |
| 500mg | $4262 | Get quote |
| 1 g | Get quote | |
| 5 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101996 |
| M.Wt: | 315.32 |
| Formula: | C20H13NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SMBA1 is a potent Bax agonist with a Ki value of 43.3 nM. SMBA1 enhances the Bax expression. SMBA1 shows anti-tumor activity. SMBA1 has the potential for the research of lung cancer[1].
In Vitro:SMBA1 induces conformational changes in Bax by blocking S184 phosphorylation, facilitating Bax insertion into mitochondrial membranes and forming Bax oligomers shows Bax agonist activity[1].
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SMBA1 (0, 0.1, 1, 5, 10 µM; 24 h) enhances the Bax expression in a dose-dependent manner in A549 cells[1].
In Vivo:SMBA1 (2, 10, 40, 60 mg/kg; i.p.; once daily for 10 days) shows anti-tumor activity in mouse[1].
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