AW-814141
CAS No. : 905285-51-0
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| Cat. No. : | HY-119298 |
| M.Wt: | 375.47 |
| Formula: | C22H25N5O |
| Purity: | >98 % |
| Solubility: |
AW-814141 is a selective and orally active p38 MAP kinase inhibitor. AW-814141 has an IC50 values of 100 nM and 158 nM for p38-α and β isoforms, respectively. AW-814141 can inhibit the production of TNF-α induced by LPS (HY-D1056). AW-814141 can inhibit paw edema in rats in a dose-dependent manner. AW-814141 exhibits anti-inflammatory activity and can be used in the research of inflammatory diseases such as rheumatoid arthritis[1].
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