FPR Agonist 43
CAS No. : 903895-98-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $190 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $570 | In-stock |
| 50mg | $825 | In-stock |
| 100mg | $1180 | In-stock |
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| Cat. No. : | HY-19574 |
| M.Wt: | 384.86 |
| Formula: | C20H21ClN4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 37.5 mg/mL (ultrasonic) |
FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2].
IC50 & Target: FPR1, FPR2/ALX[1]
In Vitro: FPR Agonist 43 (10-5-107 nM) is actively potent in the cAMP assay in FPR2/ALX over-expressing CHO cells[1].
FPR Agonist 43 is also active in the GTPγ binding assay (IC50=207±51 nM)[1].
FPR1 is the preferred receptor for FPR Agonist 43 in in both human neutrophils and possibly also in mouse cells[2].
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