7-xylosyltaxol
CAS No. : 90332-66-4
(Synonyms: 7-Xylosylpaclitaxel; Taxol-7-xyloside)
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| Cat. No. : | HY-77574 |
| M.Wt: | 986.02 |
| Formula: | C52H59NO18 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules. IC50 Value: Target: Microtubule/Tubulin Paclitaxel is a compound extracted from the Pacific yew tree with antineoplastic activity. Paclitaxel also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Paclitaxel inhibits DNA synthesis and stimulates the release of tumor necrosis factor-α. Paclitaxel induces apoptosis in murine mammary carcinoma MCA-4 and ovarian carcinoma OCA-1 tumors.
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