PFI-4
CAS No. : 900305-37-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $150 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $400 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-18664 |
| M.Wt: | 380.44 |
| Formula: | C21H24N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 26 mg/mL (ultrasonic;warming) |
PFI-4 (compound 11) is a potent and highly selective BRPF1 Bromodomain (BRPF1B) inhibitor, with an IC50 of 172 nM. PFI-4 can be used to explore the functional mechanisms of the HBO1/BRPF1 complex and to study bone loss and osteolytic malignant bone lesions[1][2]. IC50 & Target: IC50: 3.517 μM (BRPF2), >10 μM (BRD4 (1)), 0.172 μM (BRPF1B), >10 μM (TRIM24)[1]. In Vitro: PFI-4 (1.25 µM; 7 or 11 days) inhibits differentiation of human osteoclasts[1].
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