CAS No. : 9003-39-8
(Synonyms: PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000)
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| Cat. No. : | HY-B1620L |
| M.Wt: | 1000.00 |
| Formula: | (C6H9NO)n |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000 Da. Polyvinylpyrrolidone, average Mw~40000 is widely used to synthesize nanoparticles. Polyvinylpyrrolidone, average Mw~40000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc[1][2]. In Vitro:Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious fields such as paper, fibers and textiles, ceramics, and pharmaceutics due to its superior properties. Especially in pharmacy, the properties of inertness, non-toxicity, and biocompatibility make it a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc. Polyvinylpyrrolidone with different molecular weights (MWs) and concentrations is used in a variety of formulations for different purposes. The main pharmaceutical applications of Polyvinylpyrrolidone as follows: (i) improving the bioavailability and stability of drugs, (ii) improving the physicomechanical properties of preparations, (iii) adjusting the release rate of drugs, and (iv) prolonging the in vivo circulation time of liposomes[2].
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