Mardepodect
CAS No. : 898562-94-2
(Synonyms: PF-2545920)
| Size | Price | Stock |
|---|---|---|
| 5mg | $105 | In-stock |
| 10mg | $188 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $466 | In-stock |
| 100mg | $750 | In-stock |
| 500mg | $1500 | In-stock |
| 1g | $2250 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-50098 |
| M.Wt: | 392.45 |
| Formula: | C25H20N4O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 45 mg/mL |
Mardepodect (PF-2545920) is a potent, orally active and selective PDE10A inhibitor with an IC50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect can cross the blood-brain barrier[1][2]. In Vivo: In the conditioned avoidance response assay (CAR), Mardepodect (PF-2545920) is active with an ED50 of 1 mg/kg. Administration of Mardepodect (PF-2545920) to mice causes a dose dependent increase in striatal cGMP[2].
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