Gastrofensin AN 5 free base
CAS No. : 89845-16-9
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| Cat. No. : | HY-100296 |
| M.Wt: | 344.84 |
| Formula: | C19H21ClN2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent. In Vivo: Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1].
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