Tazobactam
CAS No. : 89786-04-9
(Synonyms: CL-298741; YTR-830H)
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| Cat. No. : | HY-B1418 |
| M.Wt: | 300.29 |
| Formula: | C10H12N4O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research[1][2].
In Vitro:Tazobactam (CL-298741) (5 μg/mL; 18 hours) has bactericidal activity and inhibit the growth of the bacteria in a dose-dependent manner[2].
Tazobactam (CL-298741) (1-10 μg/mL; 6 hours; Prot. vulgaris and M. morgan) inhibits various types β-lactamase activity and with ID50 values of ＜ 10 μg/mL, respectively[2].
In Vivo:Tazobactam (CL-298741) (1000 mg/kg; i.p.; four times a day, for 36 and 84 hours; BALB/c mice) decreases the number of bacteria in mice and survived in low doses[1].
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