5-Bromo-3-methylpyridin-2-ol
CAS No. : 89488-30-2
| Size | Price | Stock |
|---|---|---|
| 10g | $12 | In-stock |
| 25g | $15 | In-stock |
| 100g | $59 | In-stock |
| 500g | $294 | In-stock |
| 1000g | $470 | In-stock |
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| Cat. No. : | HY-75423 |
| M.Wt: | 188.02 |
| Formula: | C6H6BrNO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
5-Bromo-3-methylpyridin-2-ol is a 2-pyridone-based chemical intermediate that can be used for the synthesis of the ratiometric fluorescent probe NAP-t-PY. 5-Bromo-3-methylpyridin-2-ol is applicable to research on organic synthesis and fluorescent probe development[1].
In Vitro:5-Bromo-3-methylpyridin-2-ol serves as the starting material for the synthesis of the ratiometric fluorescent probe NAP-t-PY; this synthetic route involves N-benzylation to yield compound 1, two-step alkynylation to form compound 3, and Sonogashira coupling with compound 4 to synthesize NAP-t-PY[1].
5-Bromo-3-methylpyridin-2-ol undergoes N-benzylation to form compound 1; Scheme 1 shows that this step uses BnBr and K2CO3, reacts at 60 °C in DMF for 3 h, with a yield of 96%[1].
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