JNK Inhibitor VIII
CAS No. : 894804-07-0
(Synonyms: TCS JNK 6o)
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
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| Cat. No. : | HY-107598 |
| M.Wt: | 356.38 |
| Formula: | C18H20N4O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively[1].
IC50 & Target: Ki: 2 nM (JNK-1), 4 nM (JNK-2), 52 nM (JNK-3)[1]
IC50: 45 nM (JNK-1), 160 nM (JNK-2)[1]
In Vitro: JNK Inhibitor VIII (TCS JNK 6o) shows over 1000- fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ[1].
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