BIBF 1202
CAS No. : 894783-71-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $130 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $620 | In-stock |
| 100mg | $980 | In-stock |
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| Cat. No. : | HY-15992 |
| M.Wt: | 525.60 |
| Formula: | C30H31N5O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 45 mg/mL |
BIBF 1202 is the carboxylate metabolite of Nintedanib (HY-50904) which inhibits VEGFR2 kinase with an IC50 of 62 nM. IC50 & Target:IC50: 62 nM (VEGFR2)[1] In Vitro:The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide[2].
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