DMOG (Standard)
CAS No. : 89464-63-1
(Synonyms: Dimethyloxallyl Glycine (Standard))
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| Cat. No. : | HY-15893R |
| M.Wt: | 175.14 |
| Formula: | C6H9NO5 |
| Purity: | >98 % |
| Solubility: |
DMOG (Standard) is the analytical standard of DMOG. This product is intended for research and analytical applications. DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo[1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5]. IC50 & Target:HIF-1α prolyl hydroxylase[1]
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