[D-Trp7,9,10]-Substance P
CAS No. : 89430-38-6
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| Cat. No. : | HY-P1375 |
| M.Wt: | 1588.88 |
| Formula: | C79H105N21O13S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
[D-Trp7,9,10]-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1]. In Vitro: Substance P (SP)-related peptide, pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2, inhibitS the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[2].
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