Atiprosine
CAS No. : 89303-63-9
(Synonyms: AY-28228)
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| Cat. No. : | HY-119854 |
| M.Wt: | 311.46 |
| Formula: | C20H29N3 |
| Purity: | >98 % |
| Solubility: |
Atiprosine (AY-28228) is an orally effective selective α1-adrenergic receptor antagonist with a pA2 value of 8.11. Atiprosine exhibits antagonistic activity against α2-adrenergic receptors (α1-adrenergic receptor), 5-HT₂ receptors (5-HT₂ receptor), and H₁ receptors (H₁ receptor). The pA2 values for these receptors are 6.04, 6.87, and 7.32 respectively. Atiprosine has antihypertensive and hypotensive effects in rats, dogs, and monkeys. It can be used for research on cardiovascular and mental disorders.
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