SCH 12223 (free base)
CAS No. : 89109-20-6
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| Cat. No. : | HY-123388 |
| M.Wt: | 294.35 |
| Formula: | C18H18N2O2 |
| Purity: | >98 % |
| Solubility: |
SCH 12223 free base is an orally active gastroprotective agent. SCH 12223 free base exhibits gastrointestinal protective action against various noxious stimuli. SCH 12223 free base can be used for research on gastrointestinal diseases[1].
In Vivo:SCH 12223 (0.3-3 mg/kg; p.o. or i.v.) free base inhibits the ethanol-induced rat gastric lesions[1].
SCH 12223 (1-10 mg/kg; p.o.) free base lacks antisecretory activity in the pylorus-ligated rats but increases total gastric mucus[1].
SCH 12223 (10-30 mg/kg; p.o.) free base attenuates rat intestinal lesions provoked by Indomethacin (HY-14397)[1].
SCH 12223 (38 days) free base improves rat survival from Indomethacin lethality[1].
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