S3QEL-2
CAS No. : 890888-12-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $70 | In-stock |
| 50mg | $210 | In-stock |
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| Cat. No. : | HY-110282 |
| M.Wt: | 323.44 |
| Formula: | C19H25N5 |
| Purity: | >98 % |
| Solubility: | DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C) |
S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1]. In Vitro: S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1].
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