Heclin
CAS No. : 890605-54-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $32 | In-stock |
| 5mg | $80 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $250 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $620 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-110204 |
| M.Wt: | 283.32 |
| Formula: | C17H17NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Heclin is a HECT E3 ubiquitin ligases inhibitor. Heclin inhibits Smurf2, Nedd4, WWP1 (IC50 values are 6.8, 6.3, 6.9 μM) and can be used for the research of gastric cancer[1][2][3].
In Vitro:Heclin (10 μM, 1-5 days) inhibits cell viability and IGF1 signaling of BGC803 and MKN45 cell lines[1].
Heclin (7 μM, 1 h) ameliorates epinecidin-1-mediated MyD88 degradation in Raw264.7 cells[2].
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